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SHED-derived exosomes ameliorate hyposalivation caused by Sjögren's syndrome via Akt/GSK-3β/Slug-mediated ZO-1 expression

BACKGROUND: Sjögren's syndrome (SS) is an autoimmune disorder characterized by sicca syndrome and/or systemic manifestations. The treatment is still challenging. This study aimed to explore the therapeutic role and mechanism of exosomes obtained from the supernatant of stem cells derived from h...

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Detalles Bibliográficos
Autores principales: Du, Zhihao, Wei, Pan, Jiang, Nan, Wu, Liling, Ding, Chong, Yu, Guangyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617935/
https://www.ncbi.nlm.nih.gov/pubmed/37052137
http://dx.doi.org/10.1097/CM9.0000000000002610