SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9

Regulation of viral RNA biogenesis is fundamental to productive SARS-CoV-2 infection. To characterize host RNA-binding proteins (RBPs) involved in this process, we biochemically identified proteins bound to genomic and subgenomic SARS-CoV-2 RNAs. We find that the host protein SND1 binds the 5′ end o...

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Detalles Bibliográficos
Autores principales: Schmidt, Nora, Ganskih, Sabina, Wei, Yuanjie, Gabel, Alexander, Zielinski, Sebastian, Keshishian, Hasmik, Lareau, Caleb A., Zimmermann, Liv, Makroczyova, Jana, Pearce, Cadence, Krey, Karsten, Hennig, Thomas, Stegmaier, Sebastian, Moyon, Lambert, Horlacher, Marc, Werner, Simone, Aydin, Jens, Olguin-Nava, Marco, Potabattula, Ramya, Kibe, Anuja, Dölken, Lars, Smyth, Redmond P., Caliskan, Neva, Marsico, Annalisa, Krempl, Christine, Bodem, Jochen, Pichlmair, Andreas, Carr, Steven A., Chlanda, Petr, Erhard, Florian, Munschauer, Mathias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617981/
https://www.ncbi.nlm.nih.gov/pubmed/37794589
http://dx.doi.org/10.1016/j.cell.2023.09.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617981/
https://www.ncbi.nlm.nih.gov/pubmed/37794589
http://dx.doi.org/10.1016/j.cell.2023.09.002

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