BCL-3 loss sensitises colorectal cancer cells to DNA damage by targeting homologous recombination

The proto-oncogene BCL-3 is upregulated in a subset of colorectal cancers (CRC), where it has been shown to enhance tumour cell survival. However, although increased expression correlates with poor patient prognosis, the role of BCL-3 in determining therapeutic response remains largely unknown. In t...

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Detalles Bibliográficos
Autores principales: Parker, Christopher, Chambers, Adam C., Flanagan, Dustin J., Ho, Jasmine Wing Yu, Collard, Tracey J., Ngo, Greg, Baird, Duncan M., Timms, Penny, Morgan, Rhys G., Sansom, Owen J., Williams, Ann C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618080/
https://www.ncbi.nlm.nih.gov/pubmed/35468497
http://dx.doi.org/10.1016/j.dnarep.2022.103331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618080/
https://www.ncbi.nlm.nih.gov/pubmed/35468497
http://dx.doi.org/10.1016/j.dnarep.2022.103331

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