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Antipsychotic dose, dopamine D2 receptor occupancy and extrapyramidal side-effects: a systematic review and dose-response meta-analysis

Antipsychotic drugs differ in their propensity to cause extrapyramidal side-effects (EPS), but their dose-effects are unclear. Therefore, we conducted a systematic review and dose-response meta-analysis. We searched multiple electronic databases up to 20.02.2023 for fixed-dose studies investigating...

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Detalles Bibliográficos
Autores principales: Siafis, Spyridon, Wu, Hui, Wang, Dongfang, Burschinski, Angelika, Nomura, Nobuyuki, Takeuchi, Hiroyoshi, Schneider-Thoma, Johannes, Davis, John M., Leucht, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618092/
https://www.ncbi.nlm.nih.gov/pubmed/37537284
http://dx.doi.org/10.1038/s41380-023-02203-y