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Loss of spines in the prelimbic cortex is detrimental to working memory in mice with early-life adversity

Adverse experiences in early life can shape neuronal structures and synaptic function in multiple brain regions, leading to deficits of distinct cognitive functions later in life. Focusing on the pyramidal cells of the prelimbic cortex (PrL), a main subregion of the medial prefrontal cortex, the imp...

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Detalles Bibliográficos
Autores principales: Xu, Liping, Liu, Yue, Long, Jingyi, He, Xiulan, Xie, Fanbing, Yin, Qiao, Chen, Michael, Long, Dahong, Chen, Yuncai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618093/
https://www.ncbi.nlm.nih.gov/pubmed/37500828
http://dx.doi.org/10.1038/s41380-023-02197-7