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Loss of spines in the prelimbic cortex is detrimental to working memory in mice with early-life adversity
Adverse experiences in early life can shape neuronal structures and synaptic function in multiple brain regions, leading to deficits of distinct cognitive functions later in life. Focusing on the pyramidal cells of the prelimbic cortex (PrL), a main subregion of the medial prefrontal cortex, the imp...
Autores principales: | Xu, Liping, Liu, Yue, Long, Jingyi, He, Xiulan, Xie, Fanbing, Yin, Qiao, Chen, Michael, Long, Dahong, Chen, Yuncai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618093/ https://www.ncbi.nlm.nih.gov/pubmed/37500828 http://dx.doi.org/10.1038/s41380-023-02197-7 |
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