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Computer-assisted stabilization of fibroblast growth factor FGF-18

The fibroblast growth factors (FGF) family holds significant potential for addressing chronic diseases. Specifically, recombinant FGF18 shows promise in treating osteoarthritis by stimulating cartilage formation. However, recent phase 2 clinical trial results of sprifermin (recombinant FGF18) indica...

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Detalles Bibliográficos
Autores principales: Jan Vilim, Ghazalova, Tereza, Petulova, Eliska, Horackova, Aneta, Stepankova, Veronika, Chaloupkova, Radka, Bednar, David, Damborsky, Jiri, Prokop, Zbynek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618113/
https://www.ncbi.nlm.nih.gov/pubmed/37920818
http://dx.doi.org/10.1016/j.csbj.2023.10.009