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Computer-assisted stabilization of fibroblast growth factor FGF-18
The fibroblast growth factors (FGF) family holds significant potential for addressing chronic diseases. Specifically, recombinant FGF18 shows promise in treating osteoarthritis by stimulating cartilage formation. However, recent phase 2 clinical trial results of sprifermin (recombinant FGF18) indica...
Autores principales: | Jan Vilim, Ghazalova, Tereza, Petulova, Eliska, Horackova, Aneta, Stepankova, Veronika, Chaloupkova, Radka, Bednar, David, Damborsky, Jiri, Prokop, Zbynek |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618113/ https://www.ncbi.nlm.nih.gov/pubmed/37920818 http://dx.doi.org/10.1016/j.csbj.2023.10.009 |
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