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mRNA vaccine encoding Gn provides protection against severe fever with thrombocytopenia syndrome virus in mice

We developed a promising mRNA vaccine against severe fever with thrombocytopenia syndrome (SFTS), an infectious disease caused by the SFTS virus that is primarily transmitted through tick bites. Administration of lipid nanoparticle-encapsulated mRNA-Gn successfully induced neutralizing antibodies an...

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Detalles Bibliográficos
Autores principales: Kim, Jae-Yong, Jeon, Kyeongseok, Park, Sang-In, Bang, Yoo-Jin, Park, Hyeong-Jun, Kwak, Hye Won, Kim, Do-Hyung, Lee, Soo-Yeon, Choi, Eun-Jin, Cho, Nam-Hyuk, Nam, Jae-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618158/
https://www.ncbi.nlm.nih.gov/pubmed/37907507
http://dx.doi.org/10.1038/s41541-023-00771-2