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Genome-wide association analysis of plasma lipidome identifies 495 genetic associations

The human plasma lipidome captures risk for cardiometabolic diseases. To discover new lipid-associated variants and understand the link between lipid species and cardiometabolic disorders, we perform univariate and multivariate genome-wide analyses of 179 lipid species in 7174 Finnish individuals. W...

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Detalles Bibliográficos
Autores principales: Ottensmann, Linda, Tabassum, Rubina, Ruotsalainen, Sanni E., Gerl, Mathias J., Klose, Christian, Widén, Elisabeth, Simons, Kai, Ripatti, Samuli, Pirinen, Matti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618167/
https://www.ncbi.nlm.nih.gov/pubmed/37907536
http://dx.doi.org/10.1038/s41467-023-42532-8