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The possible dual role of Ang-2 in the prognosis of pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) features a dense desmoplastic stroma, which raises the intratumoral interstitial pressure leading to vascular collapse and hypoxia, inducing angiogenesis. Vascular growth factors, such as vascular endothelial growth factor (VEGF) and angiopoietin-2 (Ang-2), in...

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Detalles Bibliográficos
Autores principales: Roos-Mattila, Matilda, Kaprio, Tuomas, Mustonen, Harri, Hagström, Jaana, Saharinen, Pipsa, Haglund, Caj, Seppänen, Hanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618172/
https://www.ncbi.nlm.nih.gov/pubmed/37907568
http://dx.doi.org/10.1038/s41598-023-45194-0