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Data-driven structural analysis of small cell lung cancer transcription factor network suggests potential subtype regulators and transition pathways

Small cell lung cancer (SCLC) is an aggressive disease and challenging to treat due to its mixture of transcriptional subtypes and subtype transitions. Transcription factor (TF) networks have been the focus of studies to identify SCLC subtype regulators via systems approaches. Yet, their structures,...

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Detalles Bibliográficos
Autores principales: Ozen, Mustafa, Lopez, Carlos F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618210/
https://www.ncbi.nlm.nih.gov/pubmed/37907529
http://dx.doi.org/10.1038/s41540-023-00316-2