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Data-driven structural analysis of small cell lung cancer transcription factor network suggests potential subtype regulators and transition pathways
Small cell lung cancer (SCLC) is an aggressive disease and challenging to treat due to its mixture of transcriptional subtypes and subtype transitions. Transcription factor (TF) networks have been the focus of studies to identify SCLC subtype regulators via systems approaches. Yet, their structures,...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618210/ https://www.ncbi.nlm.nih.gov/pubmed/37907529 http://dx.doi.org/10.1038/s41540-023-00316-2 |