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Apelin is expressed in intimal smooth muscle cells and promotes their phenotypic transition

During atherosclerotic plaque formation, smooth muscle cells (SMCs) switch from a contractile/differentiated to a synthetic/dedifferentiated phenotype. We previously isolated differentiated spindle-shaped (S) and dedifferentiated rhomboid (R) SMCs from porcine coronary artery. R-SMCs express S100A4,...

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Detalles Bibliográficos
Autores principales: Cardoso Dos Santos, Luís Miguel, Azar, Pascal, Brun, Cécile, König, Stéphane, Roatti, Angela, Baertschi, Alex J., Chaabane, Chiraz, Bochaton-Piallat, Marie-Luce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618247/
https://www.ncbi.nlm.nih.gov/pubmed/37907514
http://dx.doi.org/10.1038/s41598-023-45470-z