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METTL3-mediated m6A methylation of C1qA regulates the Rituximab resistance of diffuse large B-cell lymphoma cells

Rituximab has been incorporated into the standard treatment regimen for diffuse large B-cell lymphoma (DLBCL), and induces the death of tumor cells via complement-dependent cytotoxicity (CDC). Unfortunately, the resistance of DLBCL cells to Rituximab limits its clinical usefulness. It remains unclea...

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Detalles Bibliográficos
Autores principales: Li, Junping, Zhu, Zhigang, Zhu, Yuan, Li, Jinqing, Li, Kangbao, Zhong, Weijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618261/
https://www.ncbi.nlm.nih.gov/pubmed/37907575
http://dx.doi.org/10.1038/s41420-023-01698-2