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An in situ dual-anchoring strategy for enhanced immobilization of PD-L1 to treat autoimmune diseases

Immune checkpoints play key roles in maintaining self-tolerance. Targeted potentiation of the checkpoint molecule PD-L1 through in situ manipulation offers clinical promise for patients with autoimmune diseases. However, the therapeutic effects of these approaches are often compromised by limited sp...

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Detalles Bibliográficos
Autores principales: Wang, Shenqiang, Zhang, Ying, Wang, Yanfang, Yang, Yinxian, Zhao, Sheng, Sheng, Tao, Zhang, Yuqi, Gu, Zhen, Wang, Jinqiang, Yu, Jicheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618264/
https://www.ncbi.nlm.nih.gov/pubmed/37907476
http://dx.doi.org/10.1038/s41467-023-42725-1