Continually recruited naïve T cells contribute to the follicular helper and regulatory T cell pools in germinal centers

Follicular helper T cells (T(FH)) mediate B cell selection and clonal expansion in germinal centers (GCs), and follicular regulatory T cells (T(FR)) prevent the emergence of self-reactive B cells and help to extinguish the reaction. Here we show that GC reactions continually recruit T cells from bot...

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Detalles Bibliográficos
Autores principales: Merkenschlager, Julia, Berz, Riza-Maria, Ramos, Victor, Uhlig, Maximilian, MacLean, Andrew J., Nowosad, Carla R., Oliveira, Thiago Y., Nussenzweig, Michel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618265/
https://www.ncbi.nlm.nih.gov/pubmed/37907454
http://dx.doi.org/10.1038/s41467-023-41880-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618265/
https://www.ncbi.nlm.nih.gov/pubmed/37907454
http://dx.doi.org/10.1038/s41467-023-41880-9

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