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On the possibility of the existence of orienting hydrodynamic steering effects in the kinetics of receptor–ligand association

In the vast majority of biologically relevant cases of receptor-ligand complex formation, the binding site of the receptor is a small part of its surface, and moreover, formation of a biologically active complex often requires a specific orientation of the ligand relative to the binding site. Before...

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Detalles Bibliográficos
Autor principal: Antosiewicz, Jan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618320/
https://www.ncbi.nlm.nih.gov/pubmed/37173574
http://dx.doi.org/10.1007/s00249-023-01653-0