Mammalian Nudt15 hydrolytic and binding activity on methylated guanosine mononucleotides

The Nudt15 enzyme of the NUDIX protein family is the subject of extensive study due to its action on thiopurine drugs used in the treatment of cancer and inflammatory diseases. In addition to thiopurines, Nudt15 is enzymatically active in vitro on several nucleotide substrates. It has also been sugg...

Descripción completa

Detalles Bibliográficos
Autores principales: Lukaszewicz, Maciej, Ferenc-Mrozek, Aleksandra, Kokosza, Julia, Stefaniuk, Anna, Stepinski, Janusz, Bojarska, Elzbieta, Darzynkiewicz, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618335/
https://www.ncbi.nlm.nih.gov/pubmed/37644211
http://dx.doi.org/10.1007/s00249-023-01678-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618335/
https://www.ncbi.nlm.nih.gov/pubmed/37644211
http://dx.doi.org/10.1007/s00249-023-01678-5

Ejemplares similares