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Mammalian Nudt15 hydrolytic and binding activity on methylated guanosine mononucleotides
The Nudt15 enzyme of the NUDIX protein family is the subject of extensive study due to its action on thiopurine drugs used in the treatment of cancer and inflammatory diseases. In addition to thiopurines, Nudt15 is enzymatically active in vitro on several nucleotide substrates. It has also been sugg...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618335/ https://www.ncbi.nlm.nih.gov/pubmed/37644211 http://dx.doi.org/10.1007/s00249-023-01678-5 |