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GAS-STING: a classical DNA recognition pathways to tumor therapy

Cyclic GMP-AMP synthetase (cGAS), recognized as the primary DNA sensor within cells, possesses the capability to identify foreign DNA molecules along with free DNA fragments. This identification process facilitates the production of type I IFNs through the activator of the interferon gene (STING) wh...

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Detalles Bibliográficos
Autores principales: Wang, Xinrui, Lin, Meijia, Zhu, Liping, Ye, Zhoujie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618366/
https://www.ncbi.nlm.nih.gov/pubmed/37920470
http://dx.doi.org/10.3389/fimmu.2023.1200245