Cargando…

GAS-STING: a classical DNA recognition pathways to tumor therapy

Cyclic GMP-AMP synthetase (cGAS), recognized as the primary DNA sensor within cells, possesses the capability to identify foreign DNA molecules along with free DNA fragments. This identification process facilitates the production of type I IFNs through the activator of the interferon gene (STING) wh...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Xinrui, Lin, Meijia, Zhu, Liping, Ye, Zhoujie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618366/ https://www.ncbi.nlm.nih.gov/pubmed/37920470 http://dx.doi.org/10.3389/fimmu.2023.1200245

Ejemplares similares

The cGAS/STING Pathway: A Novel Target for Cancer Therapy
por: Gan, Yu, et al.
Publicado: (2022)

cGAS/STING: novel perspectives of the classic pathway
por: Gao, Menghui, et al.
Publicado: (2020)

The Function of cGAS-STING Pathway in Treatment of Pancreatic Cancer
por: Mohseni, Ghazal, et al.
Publicado: (2021)

The cGAS-STING Pathway in Hematopoiesis and Its Physiopathological Significance
por: Liao, Weinian, et al.
Publicado: (2020)

cGAS-STING signaling pathway in intestinal homeostasis and diseases
por: Yang, Yuchen, et al.
Publicado: (2023)

Crosstalk between cGAS-STING pathway and autophagy in cancer immunity
por: Lu, Qijun, et al.
Publicado: (2023)

The Alternatively Spliced Isoforms of Key Molecules in the cGAS-STING Signaling Pathway
por: Liang, Jiaqian, et al.
Publicado: (2021)

Insights on the cGAS-STING Signaling Pathway During Herpesvirus Infections
por: Deng, Lishuang, et al.
Publicado: (2022)

A Bibliometric Analysis of the Innate Immune DNA Sensing cGAS-STING Pathway from 2013 to 2021
por: Shi, Xuan, et al.
Publicado: (2022)

The cGAS-STING Pathway in Bacterial Infection and Bacterial Immunity
por: Liu, Nanxin, et al.
Publicado: (2022)

The cGAS-STING Pathway: Novel Perspectives in Liver Diseases
por: Xu, Dongwei, et al.
Publicado: (2021)

The cGAS-STING Pathway: A Promising Immunotherapy Target
por: Ou, Liang, et al.
Publicado: (2021)

Dysregulation of the cGAS-STING Pathway in Monogenic Autoinflammation and Lupus
por: Wobma, Holly, et al.
Publicado: (2022)

Cancer immunotherapy strategies that target the cGAS-STING pathway
por: Tian, Zhuoying, et al.
Publicado: (2022)

Corrigendum: Crosstalk between cGAS-STING pathway and autophagy in cancer immunity
por: Lu, Qijun, et al.
Publicado: (2023)

African Swine Fever Virus Structural Protein p17 Inhibits cGAS-STING Signaling Pathway Through Interacting With STING
por: Zheng, Wanglong, et al.
Publicado: (2022)

Radiation-Induced Immunity and Toxicities: The Versatility of the cGAS-STING Pathway
por: Constanzo, Julie, et al.
Publicado: (2021)

cGAS-STING pathway as a potential trigger of immunosenescence and inflammaging
por: Schmitz, Carine Raquel Richter, et al.
Publicado: (2023)

Can the cGAS-STING Pathway Play a Role in the Dry Eye?
por: Ouyang, Weijie, et al.
Publicado: (2022)

Porcine cGAS-STING signaling induced autophagy inhibits STING downstream IFN and apoptosis
por: Xia, Nengwen, et al.
Publicado: (2022)

cGAS-STING Pathway Does Not Promote Autoimmunity in Murine Models of SLE
por: Motwani, Mona, et al.
Publicado: (2021)

The cGas–Sting Signaling Pathway Is Required for the Innate Immune Response Against Ectromelia Virus
por: Cheng, Wen-Yu, et al.
Publicado: (2018)

Self-DNA Sensing by cGAS-STING and TLR9 in Autoimmunity: Is the Cytoskeleton in Control?
por: Amadio, Roberto, et al.
Publicado: (2021)

Research Advances in How the cGAS-STING Pathway Controls the Cellular Inflammatory Response
por: Wan, Dongshan, et al.
Publicado: (2020)

cGAS–STING pathway in ischemia-reperfusion injury: a potential target to improve transplantation outcomes
por: Chen, Zijian, et al.
Publicado: (2023)

The battle between the innate immune cGAS-STING signaling pathway and human herpesvirus infection
por: Jin, Ximing, et al.
Publicado: (2023)

Function and regulation of cGAS-STING signaling in infectious diseases
por: Du, Yang, et al.
Publicado: (2023)

Novel insight into cGAS-STING pathway in ischemic stroke: from pre- to post-disease
por: Ma, Xiaoqi, et al.
Publicado: (2023)

Updated roles of cGAS-STING signaling in autoimmune diseases
por: Liu, Ya, et al.
Publicado: (2023)

DNA Damage and Activation of cGAS/STING Pathway Induce Tumor Microenvironment Remodeling
por: Shen, Rong, et al.
Publicado: (2022)

Cutibacterium acnes Infection Induces Type I Interferon Synthesis Through the cGAS-STING Pathway
por: Fischer, Katrin, et al.
Publicado: (2020)

Role of the cGAS/STING pathway in the control of Brucella abortus infection acquired through the respiratory route
por: Alonso Paiva, Iván M., et al.
Publicado: (2023)

Biodegradable nanoparticles induce cGAS/STING-dependent reprogramming of myeloid cells to promote tumor immunotherapy
por: Podojil, Joseph R., et al.
Publicado: (2022)

Leishmania kinetoplast DNA contributes to parasite burden in infected macrophages: Critical role of the cGAS-STING-TBK1 signaling pathway in macrophage parasitemia
por: Yilmaz, Ismail Cem, et al.
Publicado: (2022)

Inhibitory targeting cGAS-STING-TBK1 axis: Emerging strategies for autoimmune diseases therapy
por: Zhang, Min, et al.
Publicado: (2022)

The cGAS-STING Pathway Affects Vertebral Bone but Does Not Promote Intervertebral Disc Cell Senescence or Degeneration
por: Ottone, Olivia K., et al.
Publicado: (2022)

Corrigendum: The cGAS-STING pathway affects vertebral bone but does not promote intervertebral disc cell senescence or degeneration
por: Ottone, Olivia K., et al.
Publicado: (2023)

Grouper cGAS is a negative regulator of STING-mediated interferon response
por: Zhang, Luhao, et al.
Publicado: (2023)

The role of cGAS-STING signaling in pulmonary fibrosis and its therapeutic potential
por: Zhang, Jing, et al.
Publicado: (2023)

Aspirin Alleviates Particulate Matter Induced Asymptomatic Orchitis of Mice via Suppression of cGAS-STING Signaling
por: Zhu, Tengyu, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_gtltfni68bvtghrgu5v2ime93p