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A prognostic model of drug tolerant persister-related genes in lung adenocarcinoma based on single cell and bulk RNA sequencing data

BACKGROUND: Acquired resistance to targeted drugs is a major challenge in cancer. The drug-tolerant state has been proposed to be an initial step towards acquisition of real drug-resistance. Drug tolerant persister (DTP) cells are purported to survive during treatment and stay dormant for several ye...

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Detalles Bibliográficos
Autores principales: Du, Zhonghai, Zhang, Tongtong, Lin, Yanke, Dong, Guifen, Li, Aixiang, Wang, Zhiqiang, Zhang, Yongjie, Giamas, Georgios, Stebbing, Justin, Zhu, Liping, Peng, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618427/
https://www.ncbi.nlm.nih.gov/pubmed/37920509
http://dx.doi.org/10.1016/j.heliyon.2023.e20708