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Domain-PFP allows protein function prediction using function-aware domain embedding representations

Domains are functional and structural units of proteins that govern various biological functions performed by the proteins. Therefore, the characterization of domains in a protein can serve as a proper functional representation of proteins. Here, we employ a self-supervised protocol to derive functi...

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Detalles Bibliográficos
Autores principales: Ibtehaz, Nabil, Kagaya, Yuki, Kihara, Daisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618451/
https://www.ncbi.nlm.nih.gov/pubmed/37907681
http://dx.doi.org/10.1038/s42003-023-05476-9