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Heat shock protein DNAJA2 regulates transcription-coupled repair by triggering CSB degradation via chaperone-mediated autophagy

Transcription-coupled nucleotide excision repair (TC-NER) is an important genome maintenance system that preferentially removes DNA lesions on the transcribed strand of actively transcribed genes, including non-coding genes. TC-NER involves lesion recognition by the initiation complex consisting of...

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Detalles Bibliográficos
Autores principales: Huang, Yaping, Gu, Liya, Li, Guo-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618452/
https://www.ncbi.nlm.nih.gov/pubmed/37907457
http://dx.doi.org/10.1038/s41421-023-00601-8