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Cynaropicrin disrupts tubulin and c-Myc-related signaling and induces parthanatos-type cell death in multiple myeloma

The majority of blood malignancies is incurable and has unforeseeable remitting-relapsing paths in response to different treatments. Cynaropicrin, a natural sesquiterpene lactone from the edible parts of the artichoke plant, has gained increased attention as a chemotherapeutic agent. In this study,...

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Detalles Bibliográficos
Autores principales: Boulos, Joelle C., Omer, Ejlal A., Rigano, Daniela, Formisano, Carmen, Chatterjee, Manik, Leich, Ellen, Klauck, Sabine M., Shan, Le-tian, Efferth, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618500/
https://www.ncbi.nlm.nih.gov/pubmed/37344563
http://dx.doi.org/10.1038/s41401-023-01117-3