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Decreased B4GALT1 promotes hepatocellular carcinoma cell invasiveness by regulating the laminin-integrin pathway

Beta1,4-galactosyltransferases (B4GALTs) play a crucial role in several diseases, including cancer. B4GALT1 is highly expressed in the liver, and patients with mutations in B4GALT1 exhibit hepatopathy. However, the role of B4GALT1 in liver cancer remains unclear. Here, we found that B4GALT1 was sign...

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Detalles Bibliográficos
Autores principales: Chen, Po-Da, Liao, Ying-Yu, Cheng, Yu-Chia, Wu, Hsin-Yi, Wu, Yao-Ming, Huang, Min-Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618527/
https://www.ncbi.nlm.nih.gov/pubmed/37907465
http://dx.doi.org/10.1038/s41389-023-00494-y