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Targeting E3 ubiquitin ligases and their adaptors as a therapeutic strategy for metabolic diseases
Posttranslational modification of proteins via ubiquitination determines their activation, translocation, dysregulation, or degradation. This process targets a large number of cellular proteins, affecting all biological pathways involved in the cell cycle, development, growth, and differentiation. T...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618535/ https://www.ncbi.nlm.nih.gov/pubmed/37779139 http://dx.doi.org/10.1038/s12276-023-01087-w |