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Combination of genomic instability score and TP53 status for prognosis prediction in lung adenocarcinoma

The genomic instability (GI) /homologous recombination deficiency (HRD) score, calculated as the sum of the events of loss of heterozygosity (LOH), large-scale state transition (LST) and telomere allele imbalance (TAI), is used to guide the choice of treatment in several cancers, but its relationshi...

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Detalles Bibliográficos
Autores principales: Feng, Juan, Lan, Yang, Liu, Feng, Yuan, Ye, Ge, Jia, Wei, Sen, Luo, Hu, Li, Jianjun, Luo, Tao, Bian, Xiuwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618567/
https://www.ncbi.nlm.nih.gov/pubmed/37907595
http://dx.doi.org/10.1038/s41698-023-00465-x