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Combination of genomic instability score and TP53 status for prognosis prediction in lung adenocarcinoma
The genomic instability (GI) /homologous recombination deficiency (HRD) score, calculated as the sum of the events of loss of heterozygosity (LOH), large-scale state transition (LST) and telomere allele imbalance (TAI), is used to guide the choice of treatment in several cancers, but its relationshi...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618567/ https://www.ncbi.nlm.nih.gov/pubmed/37907595 http://dx.doi.org/10.1038/s41698-023-00465-x |