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Engineering a tunable micropattern‐array assay to sort single extracellular vesicles and particles to detect RNA and protein in situ

The molecular heterogeneity of extracellular vesicles (EVs) and the co‐isolation of physically similar particles, such as lipoproteins (LPs), confounds and limits the sensitivity of EV bulk biomarker characterization. Herein, we present a single‐EV and particle (siEVP) protein and RNA assay ((siEVP)...

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Detalles Bibliográficos
Autores principales: Zhang, Jingjing, Rima, Xilal Y., Wang, Xinyu, Nguyen, Luong T. H., Huntoon, Kristin, Ma, Yifan, Palacio, Paola Loreto, Nguyen, Kim Truc, Albert, Karunya, Duong‐Thi, Minh‐Dao, Walters, Nicole, Kwak, Kwang Joo, Yoon, Min Jin, Li, Hong, Doon‐Ralls, Jacob, Hisey, Colin L., Lee, Daeyong, Wang, Yifan, Ha, Jonghoon, Scherler, Kelsey, Fallen, Shannon, Lee, Inyoul, Palmer, Andre F., Jiang, Wen, Magaña, Setty M., Wang, Kai, Kim, Betty Y. S., Lee, L. James, Reátegui, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618633/
https://www.ncbi.nlm.nih.gov/pubmed/37908159
http://dx.doi.org/10.1002/jev2.12369