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Dissecting the Mechanisms Underlying the Cytokine Release Syndrome (CRS) Mediated by T-Cell Bispecific Antibodies
PURPOSE: Target-dependent TCB activity can result in the strong and systemic release of cytokines that may develop into cytokine release syndrome (CRS), highlighting the need to understand and prevent this complex clinical syndrome. EXPERIMENTAL DESIGN: We explored the cellular and molecular players...
Autores principales: | Leclercq-Cohen, Gabrielle, Steinhoff, Nathalie, Albertí Servera, Llucia, Nassiri, Sina, Danilin, Sabrina, Piccione, Emily, Yángüez, Emilio, Hüsser, Tamara, Herter, Sylvia, Schmeing, Stephan, Gerber, Petra, Schwalie, Petra, Sam, Johannes, Briner, Stefanie, Jenni, Sylvia, Bianchi, Roberta, Biehl, Marlene, Cremasco, Floriana, Apostolopoulou, Katerina, Haegel, Hélène, Klein, Christian, Umaña, Pablo, Bacac, Marina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618647/ https://www.ncbi.nlm.nih.gov/pubmed/37379429 http://dx.doi.org/10.1158/1078-0432.CCR-22-3667 |
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