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Targeted Inhibition of lncRNA Malat1 Alters the Tumor Immune Microenvironment in Preclinical Syngeneic Mouse Models of Triple-Negative Breast Cancer

Long noncoding RNAs (lncRNA) play an important role in gene regulation in both normal tissues and cancer. Targeting lncRNAs is a promising therapeutic approach that has become feasible through the development of gapmer antisense oligonucleotides (ASO). Metastasis-associated lung adenocarcinoma trans...

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Detalles Bibliográficos
Autores principales: Adewunmi, Oluwatoyosi, Shen, Yichao, Zhang, Xiang H.-F., Rosen, Jeffrey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618655/
https://www.ncbi.nlm.nih.gov/pubmed/37603945
http://dx.doi.org/10.1158/2326-6066.CIR-23-0045