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Loss of histone reader Phf7 leads to immune pathways activation via endogenous retroviruses during spermiogenesis

Genetic studies have elucidated the critical roles of Phf7 in germline development in animals; however, the exact etiology of Phf7 mutations leading to male infertility and the possibility of mechanism-based therapy are still unclear and warrant further investigation. Using the Phf7 knockout mouse m...

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Detalles Bibliográficos
Autores principales: Cheng, Jianxing, Li, Tongtong, Zheng, Zhongjie, Zhang, Xueguang, Cao, Mengyang, Tang, Wenhao, Hong, Kai, Zheng, Rui, Shao, Jichun, Zhao, Xiaomiao, Jiang, Hui, Xu, Wenming, Lin, Haocheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618686/
https://www.ncbi.nlm.nih.gov/pubmed/37920670
http://dx.doi.org/10.1016/j.isci.2023.108030