The PWWP domain and the evolution of unique DNA methylation toolkits in Hymenoptera

DNMT3 in Hymenoptera has a unique duplication of the essential PWWP domain. Using GST-tagged PWWP fusion proteins and histone arrays we show that these domains have gained new properties and represent the first case of PWWP domains binding to H3K27 chromatin modifications, including H3K27me3, a key...

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Detalles Bibliográficos
Autores principales: Kucharski, Robert, Ellis, Nancy, Jurkowski, Tomasz P., Hurd, Paul J., Maleszka, Ryszard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618690/
https://www.ncbi.nlm.nih.gov/pubmed/37920666
http://dx.doi.org/10.1016/j.isci.2023.108193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618690/
https://www.ncbi.nlm.nih.gov/pubmed/37920666
http://dx.doi.org/10.1016/j.isci.2023.108193

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