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Detachable-dissolvable-microneedle as a potent subunit vaccine delivery device that requires no cold-chain

Although vaccine administration by microneedles has been demonstrated, delivery reliability issues have prevented their implementation. Through an ex vivo porcine skin experiment, we show visual evidence indicating that detachable dissolvable microneedles (DDMN) can deposit cargo into the dermis wit...

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Detalles Bibliográficos
Autores principales: Phoka, Theerapat, Thanuthanakhun, Naruchit, Visitchanakun, Peerapat, Dueanphen, Narintorn, Wanichwecharungruang, Nisha, Leelahavanichkul, Asada, Palaga, Tanapat, Ruxrungtham, Kiat, Wanichwecharungruang, Supason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618702/
https://www.ncbi.nlm.nih.gov/pubmed/37920235
http://dx.doi.org/10.1016/j.jvacx.2023.100398