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Detachable-dissolvable-microneedle as a potent subunit vaccine delivery device that requires no cold-chain
Although vaccine administration by microneedles has been demonstrated, delivery reliability issues have prevented their implementation. Through an ex vivo porcine skin experiment, we show visual evidence indicating that detachable dissolvable microneedles (DDMN) can deposit cargo into the dermis wit...
Autores principales: | Phoka, Theerapat, Thanuthanakhun, Naruchit, Visitchanakun, Peerapat, Dueanphen, Narintorn, Wanichwecharungruang, Nisha, Leelahavanichkul, Asada, Palaga, Tanapat, Ruxrungtham, Kiat, Wanichwecharungruang, Supason |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618702/ https://www.ncbi.nlm.nih.gov/pubmed/37920235 http://dx.doi.org/10.1016/j.jvacx.2023.100398 |
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