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Single-nucleus RNA sequencing reveals heterogenous microenvironments and specific drug response between cervical squamous cell carcinoma and adenocarcinoma

BACKGROUND: Cervical squamous cell carcinoma (CSCC) and adenocarcinoma (CAde) are two major pathological types of cervical cancer (CC), but their high-resolution heterogeneity of tumor and immune microenvironment remains elusive. METHODS: Here, we performed single-nucleus RNA sequencing (snRNA-seq)...

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Detalles Bibliográficos
Autores principales: Lin, Shitong, Sun, Yuanhui, Cao, Canhui, Zhu, Zhixian, Xu, Yashi, Liu, Binghan, Hu, Bai, Peng, Ting, Zhi, Wenhua, Xu, Miaochun, Ding, Wencheng, Ren, Fang, Ma, Ding, Li, Guoliang, Wu, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618708/
https://www.ncbi.nlm.nih.gov/pubmed/37879219
http://dx.doi.org/10.1016/j.ebiom.2023.104846