Parkin Deficiency Suppresses Antigen Presentation to Promote Tumor Immune Evasion and Immunotherapy Resistance

Parkin is an E3 ubiquitin ligase, which plays a key role in the development of Parkinson disease. Parkin defects also occur in numerous cancers, and a growing body of evidence indicates that Parkin functions as a tumor suppressor that impedes a number of cellular processes involved in tumorigenesis....

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Detalles Bibliográficos
Autores principales: Perales-Linares, Renzo, Leli, Nektaria Maria, Mohei, Hesham, Beghi, Silvia, Rivera, Osvaldo D., Kostopoulos, Nektarios, Giglio, Andrea, George, Subin S., Uribe-Herranz, Mireia, Costabile, Francesca, Pierini, Stefano, Pustylnikov, Sergei, Skoufos, Giorgos, Barash, Yoseph, Hatzigeorgiou, Artemis G., Koumenis, Constantinos, Maity, Amit, Lotze, Michael T., Facciabene, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Cancer Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618737/
https://www.ncbi.nlm.nih.gov/pubmed/37578274
http://dx.doi.org/10.1158/0008-5472.CAN-22-2499

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618737/
https://www.ncbi.nlm.nih.gov/pubmed/37578274
http://dx.doi.org/10.1158/0008-5472.CAN-22-2499

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