SHP2: A Pleiotropic Target at the Interface of Cancer and Its Microenvironment

The protein phosphatase SHP2/PTPN11 has been reported to be a key modulator of proliferative pathways in a wide range of malignancies. Intriguingly, SHP2 has also been described as a critical regulator of the tumor microenvironment. Based on this evidence SHP2 is considered a multifaceted target in...

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Detalles Bibliográficos
Autores principales: Sodir, Nicole M., Pathria, Gaurav, Adamkewicz, Joanne I., Kelley, Elizabeth H., Sudhamsu, Jawahar, Merchant, Mark, Chiarle, Roberto, Maddalo, Danilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618746/
https://www.ncbi.nlm.nih.gov/pubmed/37682219
http://dx.doi.org/10.1158/2159-8290.CD-23-0383

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618746/
https://www.ncbi.nlm.nih.gov/pubmed/37682219
http://dx.doi.org/10.1158/2159-8290.CD-23-0383

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