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Salidroside attenuates atrial fibrosis and atrial fibrillation vulnerability induced by angiotensin-II through inhibition of LOXL2-TGF-β1-Smad2/3 pathway

AIMS AND OBJECTIVES: Salidroside (SAL), an active component isolated from the Chinese plant Rose Rhodiola, has anti-inflammatory, antioxidant, anti-cancer, neuroprotective, and renal protective properties. Atrial fibrosis developed due to angiotensin II (Ang II) plays a crucial function in developin...

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Detalles Bibliográficos
Autores principales: Hai, Zhen, Wu, Yingbiao, Ning, Zhongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618763/
https://www.ncbi.nlm.nih.gov/pubmed/37920527
http://dx.doi.org/10.1016/j.heliyon.2023.e21220