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Integrated workflow for discovery of microprotein-coding small open reading frames

Small open reading frame (smORF)-encoded microproteins, proteins containing less than 100–150 amino acids, are an emerging class of functional biomolecules. Here, we present a protocol for identifying translated smORFs in mammalian systems genome wide. We describe steps for generation of ribosome pr...

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Detalles Bibliográficos
Autores principales: Cao, Kevin, Hajy Heydary, Yasamin, Tong, Gregory, Martinez, Thomas Farid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618807/
https://www.ncbi.nlm.nih.gov/pubmed/37874679
http://dx.doi.org/10.1016/j.xpro.2023.102649