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Changes in liver metabolic pathways demonstrate efficacy of the combined dietary and microbial therapeutic intervention in MASLD mouse model

OBJECTIVE: Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as non-alcoholic fatty liver disease (NAFLD), is the most prevalent liver disease globally, yet no therapies are approved. The effects of Escherichia coli Nissle 1917 expressing aldafermin, an engineered anal...

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Detalles Bibliográficos
Autores principales: Iannone, Valeria, Babu, Ambrin Farizah, Lok, Johnson, Gómez-Gallego, Carlos, D'Auria, Giuseppe, Vazquez-Uribe, Ruben, Vaaben, Troels Holger, Bongers, Mareike, Mikkonen, Santtu, Vaittinen, Maija, Tikkanen, Ida, Kettunen, Mikko, Klåvus, Anton, Sehgal, Ratika, Kaminska, Dorota, Pihlajamaki, Jussi, Hanhineva, Kati, El-Nezami, Hani, Sommer, Morten Otto Alexander, Kolehmainen, Marjukka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618820/
https://www.ncbi.nlm.nih.gov/pubmed/37839774
http://dx.doi.org/10.1016/j.molmet.2023.101823