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HArmonized single-cell RNA-seq Cell type Assisted Deconvolution (HASCAD)

BACKGROUND: Cell composition deconvolution (CCD) is a type of bioinformatic task to estimate the cell fractions from bulk gene expression profiles, such as RNA-seq. Many CCD models were developed to perform linear regression analysis using reference gene expression signatures of distinct cell types....

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Detalles Bibliográficos
Autores principales: Chiu, Yen-Jung, Ni, Chung-En, Huang, Yen-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619225/
https://www.ncbi.nlm.nih.gov/pubmed/37907883
http://dx.doi.org/10.1186/s12920-023-01674-w