Extracellular matrix modulates the spatial hepatic features in hepatocyte-like cells derived from human embryonic stem cells

BACKGROUND: Human pluripotent stem cell (hPSC)-derived hepatocyte-like cells (HLCs) can provide a valuable in vitro model for disease modelling and drug development. However, generating HLCs with characteristics comparable to hepatocytes in vivo is challenging. Extracellular matrix (ECM) plays an im...

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Detalles Bibliográficos
Autores principales: Farhan, Faiza, Trivedi, Manjari, Di Wu, Priscilla, Cui, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619266/
https://www.ncbi.nlm.nih.gov/pubmed/37907977
http://dx.doi.org/10.1186/s13287-023-03542-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619266/
https://www.ncbi.nlm.nih.gov/pubmed/37907977
http://dx.doi.org/10.1186/s13287-023-03542-x

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