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Deep learning-enabled natural language processing to identify directional pharmacokinetic drug–drug interactions

BACKGROUND: During drug development, it is essential to gather information about the change of clinical exposure of a drug (object) due to the pharmacokinetic (PK) drug-drug interactions (DDIs) with another drug (precipitant). While many natural language processing (NLP) methods for DDI have been pu...

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Detalles Bibliográficos
Autores principales: Zirkle, Joel, Han, Xiaomei, Racz, Rebecca, Samieegohar, Mohammadreza, Chaturbedi, Anik, Mann, John, Chakravartula, Shilpa, Li, Zhihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619324/
https://www.ncbi.nlm.nih.gov/pubmed/37914988
http://dx.doi.org/10.1186/s12859-023-05520-9