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Atypical homodimerization revealed by the structure of the (S)-enantioselective haloalkane dehalogenase DmmarA from Mycobacterium marinum
Haloalkane dehalogenases (HLDs) are a family of α/β-hydrolase fold enzymes that employ S(N)2 nucleophilic substitution to cleave the carbon–halogen bond in diverse chemical structures, the biological role of which is still poorly understood. Atomic-level knowledge of both the inner organization and...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619424/ https://www.ncbi.nlm.nih.gov/pubmed/37860958 http://dx.doi.org/10.1107/S2059798323006642 |