A lipid-associated macrophage lineage rewires the spatial landscape of adipose tissue in early obesity

Adipose tissue macrophage (ATM) infiltration is associated with adipose tissue dysfunction and insulin resistance in mice and humans. Recent single-cell data highlight increased ATM heterogeneity in obesity but do not provide a spatial context for ATM phenotype dynamics. We integrated single-cell RN...

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Detalles Bibliográficos
Autores principales: Stansbury, Cooper M., Dotson, Gabrielle A., Pugh, Harrison, Rehemtulla, Alnawaz, Rajapakse, Indika, Muir, Lindsey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Technical Advance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619435/
https://www.ncbi.nlm.nih.gov/pubmed/37651193
http://dx.doi.org/10.1172/jci.insight.171701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619435/
https://www.ncbi.nlm.nih.gov/pubmed/37651193
http://dx.doi.org/10.1172/jci.insight.171701

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