Cargando…

A lipid-associated macrophage lineage rewires the spatial landscape of adipose tissue in early obesity

Adipose tissue macrophage (ATM) infiltration is associated with adipose tissue dysfunction and insulin resistance in mice and humans. Recent single-cell data highlight increased ATM heterogeneity in obesity but do not provide a spatial context for ATM phenotype dynamics. We integrated single-cell RN...

Descripción completa

Detalles Bibliográficos
Autores principales:	Stansbury, Cooper M., Dotson, Gabrielle A., Pugh, Harrison, Rehemtulla, Alnawaz, Rajapakse, Indika, Muir, Lindsey A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2023
Materias:	Technical Advance
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619435/ https://www.ncbi.nlm.nih.gov/pubmed/37651193 http://dx.doi.org/10.1172/jci.insight.171701

Ejemplares similares

Functional organization of the maternal and paternal human 4D Nucleome
por: Lindsly, Stephen, et al.
Publicado: (2021)

Forward-in-Time, Spatially Explicit Modeling Software to Simulate Genetic Lineages Under Selection
por: Currat, Mathias, et al.
Publicado: (2016)

Double kissing inflation outside the stent secures the patency of small side branch without rewiring
por: Yang, Hongbo, et al.
Publicado: (2021)

Plastid proteome prediction for diatoms and other algae with secondary plastids of the red lineage
por: Gruber, Ansgar, et al.
Publicado: (2015)

Spatial cluster detection using dynamic programming
por: Sverchkov, Yuriy, et al.
Publicado: (2012)

Single cell analysis of M. tuberculosis phenotype and macrophage lineages in the infected lung
por: Pisu, Davide, et al.
Publicado: (2021)

Half-body MRI volumetry of abdominal adipose tissue in patients with obesity
por: Linder, Nicolas, et al.
Publicado: (2019)

Fusion transcript detection using spatial transcriptomics
por: Friedrich, Stefanie, et al.
Publicado: (2020)

Deciphering multi-way interactions in the human genome
por: Dotson, Gabrielle A., et al.
Publicado: (2022)

Predicting future climate at high spatial and temporal resolution
por: Maclean, Ilya M. D.
Publicado: (2019)

Rapid Lineage Assignment of Severe Acute Respiratory Syndrome Coronavirus 2 Cases through Automated Library Preparation, Sequencing, and Bioinformatic Analysis
por: Gorzalski, Andrew J., et al.
Publicado: (2023)

Single-cell landscape analysis unravels molecular programming of the human B cell compartment in chronic GVHD
por: Poe, Jonathan C., et al.
Publicado: (2023)

“Spatial heterogeneity of environmental risk in randomized prevention trials: consequences and modeling”
por: Guindo, Abdoulaye, et al.
Publicado: (2019)

Adipose-derived stem cells (MYSTEM® EVO Technology) as a treatment for complex transsphincteric anal fistula
por: Lobascio, P., et al.
Publicado: (2018)

Inter and intra-reliability of ultrasonography for the measurement of abdominal subcutaneous & visceral adipose tissue thickness at 12 weeks gestation
por: Cremona, Alexandra, et al.
Publicado: (2019)

EPIREGULIN creates a developmental niche for spatially organized human intestinal enteroids
por: Childs, Charlie J., et al.
Publicado: (2023)

High inter-observer reliability in standardized ultrasound measurements of subcutaneous adipose tissue in children aged three to six years
por: Kelso, A., et al.
Publicado: (2020)

Spatial metabolomics reveals upregulation of several pyrophosphate-producing pathways in cortical bone of Hyp mice
por: Buck, Achim, et al.
Publicado: (2022)

A split green fluorescent protein system to enhance spatial and temporal sensitivity of translating ribosome affinity purification
por: Dinkeloo, Kasia, et al.
Publicado: (2022)

CoGNaC: A Chaste Plugin for the Multiscale Simulation of Gene Regulatory Networks Driving the Spatial Dynamics of Tissues and Cancer
por: Rubinacci, Simone, et al.
Publicado: (2015)

Reliability of quantifying the spatial distribution of fatty infiltration in lumbar paravertebral muscles using a new segmentation method for T1-weighted MRI
por: Mhuiris, Áine Ni, et al.
Publicado: (2016)

Development of 3D method to assess intramuscular spatial distribution of fat infiltration in patients with rotator cuff tear: reliability and concurrent validity
por: Khanna, Rajan, et al.
Publicado: (2019)

Rewiring the transcriptional circuitries in cancer by endogenous retroviruses
por: Li, Li, et al.
Publicado: (2022)

Lineage-specific regulation of inducible and constitutive mast cells in allergic airway inflammation
por: Derakhshan, Tahereh, et al.
Publicado: (2020)

SWAMP: Sliding Window Alignment Masker for PAML
por: Harrison, Peter W, et al.
Publicado: (2014)

Touchdown General Primer (GP5+/GP6+) PCR and optimized sample DNA concentration support the sensitive detection of human papillomavirus
por: Evans, Mark F, et al.
Publicado: (2005)

Landscape of mast cell populations across organs in mice and humans
por: Tauber, Marie, et al.
Publicado: (2023)

Identification of risk factors for hospital admission using multiple-failure survival models: a toolkit for researchers
por: Westbury, Leo D., et al.
Publicado: (2016)

Novel methods for microCT-based analyses of vasculature in the renal cortex reveal a loss of perfusable arterioles and glomeruli in eNOS-/- mice
por: Perrien, Daniel S., et al.
Publicado: (2016)

Resident macrophage subpopulations occupy distinct microenvironments in the kidney
por: Cheung, Matthew D., et al.
Publicado: (2022)

A framework for extending trial design to facilitate missing data sensitivity analyses
por: Mason, Alexina J., et al.
Publicado: (2020)

Statistical adjustment of genotyping error in a case–control study of childhood leukaemia
por: Cooper, Matthew N, et al.
Publicado: (2012)

A sensitive flow cytometric methodology for studying the binding of L. chagasi to canine peritoneal macrophages
por: Gonçalves, Ricardo, et al.
Publicado: (2005)

Imaging Proteolytic Activities in Mouse Models of Cancer
por: Pal, Anupama, et al.
Publicado: (2018)

Spatial mapping reveals granuloma diversity and histopathological superstructure in human tuberculosis
por: Sawyer, Andrew J., et al.
Publicado: (2023)

Rearrangement of T Cell genome architecture regulates GVHD
por: Sun, Yaping, et al.
Publicado: (2022)

Integration of spatial and single-cell transcriptomics localizes epithelial cell–immune cross-talk in kidney injury
por: Ferreira, Ricardo Melo, et al.
Publicado: (2021)

TCF7L2 silencing results in altered gene expression patterns accompanied by local genomic reorganization
por: Brown, Markus A., et al.
Publicado: (2021)

Interventional microadhesiolysis: A new nonsurgical release technique for adhesive capsulitis of the shoulder
por: Ahn, Kang, et al.
Publicado: (2008)

Multiple strand displacement amplification of mitochondrial DNA from clinical samples
por: Maragh, Samantha, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_i2e1tlkbvngghtgl82g07b14qd