ST6GAL1 sialyltransferase promotes acinar to ductal metaplasia and pancreatic cancer progression

The role of aberrant glycosylation in pancreatic ductal adenocarcinoma (PDAC) remains an under-investigated area of research. In this study, we determined that ST6 β-galactoside α2,6 sialyltransferase 1 (ST6GAL1), which adds α2,6-linked sialic acids to N-glycosylated proteins, was upregulated in pat...

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Detalles Bibliográficos
Autores principales: Bhalerao, Nikita, Chakraborty, Asmi, Marciel, Michael P., Hwang, Jihye, Britain, Colleen M., Silva, Austin D., Eltoum, Isam E., Jones, Robert B., Alexander, Katie L., Smythies, Lesley E., Smith, Phillip D., Crossman, David K., Crowley, Michael R., Shin, Boyoung, Harrington, Laurie E., Yan, Zhaoqi, Bethea, Maigen M., Hunter, Chad S., Klug, Christopher A., Buchsbaum, Donald J., Bellis, Susan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619436/
https://www.ncbi.nlm.nih.gov/pubmed/37643018
http://dx.doi.org/10.1172/jci.insight.161563

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619436/
https://www.ncbi.nlm.nih.gov/pubmed/37643018
http://dx.doi.org/10.1172/jci.insight.161563

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