Structural snapshots of Mycobacterium tuberculosis enolase reveal dual mode of 2PG binding and its implication in enzyme catalysis

Enolase, a ubiquitous enzyme, catalyzes the reversible conversion of 2-phospho­glycerate (2PG) to phospho­enolpyruvate (PEP) in the glycolytic pathway of organisms of all three domains of life. The underlying mechanism of the 2PG to PEP conversion has been studied in great detail in previous work, h...

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Detalles Bibliográficos
Autores principales: Ahmad, Mohammed, Jha, Bhavya, Bose, Sucharita, Tiwari, Satish, Dwivedy, Abhisek, Kar, Deepshikha, Pal, Ravikant, Mariadasse, Richard, Parish, Tanya, Jeyakanthan, Jeyaraman, Vinothkumar, Kutti R., Biswal, Bichitra Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2023
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619443/
https://www.ncbi.nlm.nih.gov/pubmed/37860976
http://dx.doi.org/10.1107/S2052252523008485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619443/
https://www.ncbi.nlm.nih.gov/pubmed/37860976
http://dx.doi.org/10.1107/S2052252523008485

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